Revolution and reformation as experienced in Iran is a noteworthy topic which can be studied from several aspects. This article is to study the typology of meanings and applications of reform in the Quran, approaches and strategies for reforming individuals and societies from the perspective of revelations, and the relationship between revolution and reformation. From a Quranic viewpoint, reform is the basis of any movement to make human living environment safe and healthy, which is rooted in the reformation movements of the prophets. Reform is used in the holy Quran with two clear meanings: reconciliation and removing corruptions. Depending on the degree of corruption, different cultural and non-cultural strategies are suggested to remove economic, social, political and cultural corruptions and shortcomings.